Silva CAM, Bois MF

Language: Spanish
References: 12
Page: 241-244
PDF size: 248.56 Kb.

ABSTRACT

Hypopituitarism is due to the deficiency of one or more pituitary hormones; it may be congenital or acquired. The incidence of the congenital form is low, estimated between 1/4,000 and 1/8,000 live births. We present the case of a one-month-old male infant hospitalized for episodes of severe hypoglycemia, seizures, prolonged jaundice as well as cleft palate, umbilical hernia, micropenis, and short stature. The diagnosis was confirmed by showing a deficiency of corticotropin (ACTH), thyroid stimulating hormone (TSH), gonadotropins, growth hormone (GH) and prolactin. The neuroanatomic defect by nuclear magnetic resonance informed infrachiasmatic ectopic neurohypophysis. Hormone replacement therapy was started, with resolution of symptoms and good evolution in the follow-up. Early diagnosis of congenital hypopituitarism is essential to prevent damage to cognitive function, growth deficits, and metabolic abnormalities.

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