Arboine-Aguirre LA, Galván-García JE, Palacios-Rodríguez JM, Guzmán-Ramírez D

Language: Spanish
References: 30
Page: 320-326
PDF size: 201.82 Kb.

ABSTRACT

Introduction: The significance of troponin I (Tn-I) elevation after percutaneous coronary intervention (PCI) is the subject of debate. Objective: To determine cardiovascular prognosis associated with Tn-I elevation one year after successful elective PCI. Methods: Observational, retrospective, longitudinal study. Patients who underwent successful elective PCI were included and divided in two groups: with and without Tn-I elevation, in order to compare the occurrence of major adverse cardiac events (MACE) at 1 year; post-PCI Tn-I was correlated with demographic and angiographic characteristics. Results: Tn-I elevation was detected in 32 patients (35.2%). Elevation was more common in patients with multivascular and more complex coronary artery disease, and with peri-PCI complications. MACE incidence at one year was higher in the elevated Tn-I group (25% vs. 3.4%; p = 0.002). Independent predictors of MACE were Tn-I 5-fold elevation from normal value (OR: 7.5; 95% CI: 1.25-45; p = 0.027) and peri-PCI complications (OR: 7.5; 95% CI: 1.25-45; p = 0.027). Conclusions: In patients with stable coronary artery disease, Tn-I elevation after successful elective PCI is associated with adverse cardiac events at 1 year, more extensive and complex coronary artery disease and peri-PCI complications.

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