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ISSN 2594-1518 (Electronic)
ISSN 1405-0099 (Print)

2006, Number 2

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Cir Gen 2006; 28 (2)

Retroperitoneal sarcomas

Medina-Villaseñor EA, Martínez-Macías R, Díaz-Rodríguez L, Barra- Martínez R, Garza-Navarro JM, Quezada-Adame I, Neyra-Ortiz E

Language: Spanish
References: 21
Page: 77-82
PDF size: 124.29 Kb.


ABSTRACT

Objective: To analyze our experience in the surgical treatment of retroperitoneal soft-tissue sarcoma and the prognostic factors.
Setting: Department of Mixed Tumors, Oncology Service, General Hospital of Mexico.
Design: Retrospective, transversal, descriptive.
Methods: We analyzed 59 patients who were treated through surgery for retroperitoneal soft-tissue sarcoma from January 1990 to December 2002. The prognostic factors were analyzed.
Results: Patients corresponded to 31 men and 28 women, average age of 47 years (range 17 to 75). The most common symptom was abdominal pain. Liposarcoma (44%) was the most common. Malignancy was graded as high in 66% and low in 34%. A considerable number of tumor diameters were larger than 20 cm (79%). Complete resection of the tumor was achieved in 28 (47.6%), partial or palliative resection corresponded to 23 (38.9%) and biopsy only was performed in 8 (13.5%). In block resection of the surrounding organ or organs was required in 28 cases. The kidney was the most commonly resected organ. Incomplete resection, unresectability, high grade and age were the factors most consistently shown to be prognostic for poor survival. Conclusions: Surgery represents the primary treatment of retroperitoneal sarcomas. The best long-term outcomes are associated with margin-free resections. The role of adjuvant therapy remains unclear and needs further clinical trials.


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