2018, Number 3
Irregular erythrocyte antibodies detected at State Center of Blood Transfusion of Chihuahua State, Mexico
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ABSTRACTBackground: The State Center of Blood Transfusion (CETS) of the state of Chihuahua is responsible for the donation and altruistic distribution of blood and derivatives in Chihuahua, as well as the detection of probable donors with transmissible infectious processes, and occasionally the meeting of antibodies irregular erythrocytes prior to a blood transfusion.
Objective: To describe la presence of irregular erythrocyte antibodies and the related diseases.
Material and Method: An observational, descriptive and retrospective study carried out in the CETS of Chihuahua that describes the frequency of irregular erythrocyte antibodies detected from 2010 to 2015, relating them to blood type, gender, age and clinical factors.
Results: A total of 152 records with a positive result of irregular antibodies were located out of a total of 45,878 studies conducted in the mentioned period. The data analyzed show that the female sex had a prevalence of alloantibodies of 78.2% compared to men (p ‹ 0.0001); 70.5% of people were over 30 years old; 35.1% of the patients had a positive transfusion history. Irregular anti-D antibody appeared in 21.7% of cases, being the most frequent in females (p ‹ 0.002). The most probable genotype R1r was the most prevalent in our population.
Conclusions: Knowledge of the association between the clinical conditions of patients and alloimmunization will lead to a better understanding and management of transfusion medicine.
Fatalities reported to FDA following blood collection and transfusion. Annual summary for fiscal year 2013. Actualizado el 10 de junio de 2015. Revisado el 20 de septiembre de 2017. Disponible en: http://www.fda.gov/BiologicsBloodVaccines/ SafetyAvailability/ReportaProblem/Transfusion- DonationFatalities/ucm391574.htm.