medigraphic.com
SPANISH

Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2019, Number 02

<< Back Next >>

Ginecol Obstet Mex 2019; 87 (02)

Clinical and epidemiological profile of primary ovarian failure in gynecological endocrine consultation in two health institutions in the city of Medellin, Colombia

Martínez-Sánchez LM, Gómez-Otálvaro MA, Pérez-Palacio MI, Jaramillo-Jaramillo LI, Thowinson-Hernández MC, Hormaza-Ángel MP
Full text How to cite this article

Language: Spanish
References: 7
Page: 110-115
PDF size: 206.31 Kb.


Key words:

Primary ovarian failure, Menarche, Amenorrhea, Secondary amenorrhea.

ABSTRACT

Objective: To determine the clinical and epidemiological profile of primary ovarian failure in gynecological endocrine consultation in two health institutions in the city of Medellin.
Materials and Methods: retrospective cross-sectional descriptive study, in which the study population were adult women with primary ovarian failure who attended the endocrinological medical consultation from 2017 to 2018. The source of the information were clinical histories of patients with primary ovarian failure who attended this consultation. For the analysis, absolute and relative frequencies were calculated for the qualitative variables, for the quantitative ones, the median was used.
Results: twenty-five women who met the eligibility criteria were included; The average age of the patients was 32.96 years. The mean age of menarche and definitive amenorrhea of the patients was 12.05 years and 28.57 years respectively, at approximately 28.73 years of age, the patients were diagnosed with primary ovarian insufficiency, the lowest and highest age of diagnosis was at 13 and 42 years respectively. 21/25 patients had secondary amenorrhea, 14/25 of the patients had regular cycles. The most common symptoms were heats 11/25, sweating (8/25) and depression (5/25). lowest and highest age of diagnosis was at 13 and 42 years respectively. 21/25 patients had secondary amenorrhea, 14/25 of the patients had regular cycles. The most common symptoms were heats 11/25, sweating (8/25) and depression (5/25).
Conclusions: Women with primary ovarian failure had a clinical profile with wide variation regarding the development of the disease, however, they match in most symptoms and signs. It’s important to continue studying and expanding the information about epidemiology in national and international context.


REFERENCES

  1. Chen A, et al. Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum Mol Genet. 2018;27(11):1913-26. https://doi.org/10.1093/ hmg/ddy098

  2. Christ JP, et al. Estrogen deprivation and cardiovascular disease risk in primary ovarian insufficiency. Fertil Steril. 2018;109(4):594-600.e1. https://doi.org/10.1016/j.fertnstert. 2017.11.035

  3. van Erven B, et al. Fertility in adult women with classic galactosemia and primary ovarian insufficiency. Fertil Steril. 2017;108(1):168-74. https://doi.org/10.1016/j. fertnstert.2017.05.013

  4. Chaloutsou K, et al. Premature Ovarian Insufficiency: An Adolescent Series. J Pediatr Adolesc Gynecol. 2017;30(6):615-19. https://doi.org/10.1016/j. jpag.2017.04.003

  5. Christofolini DM, et al. How polymorphic markers contribute to genetic diseases in different populations? The study of inhibin A for premature ovarian insufficiency. Einstein (Sao Paulo). 2017;15(3):269-72. http://dx.doi.org/10.1590/ s1679-45082017ao4052

  6. Guzel Y, et al. Menstrual cycle characteristics of young females with occult primary ovarian insufficiency at initial diagnosis and one-year follow-up with serum amh level and antral follicle count. PLoS One. 2017;12(11):e0188334. https://doi.org/10.1371/journal.pone.0188334

  7. Kanj RV, et al. Evaluation and Management of Primary Ovarian Insufficiency in Adolescents and Young Adults. J Pediatr Adolesc Gynecol. 2018;31(1):13-18. https://doi. org/10.1016/j.jpag.2017.07.005




2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Ginecol Obstet Mex. 2019;87