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Ginecología y Obstetricia de México

Federación Mexicana de Ginecología y Obstetricia, A.C.
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2019, Number 08

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Ginecol Obstet Mex 2019; 87 (08)

Perinatal outcomes in newborns of pregnant women infected with Zika virus

González-Méndez RP, Fierros-Adame MM, Domínguez-Morales E, Martínez-Hernández CM
Full text How to cite this article

Language: Spanish
References: 17
Page: 543-548
PDF size: 359.52 Kb.


Key words:

Pregnancy, Intection, Zika virus, Gestational age, Trisomy 18.

ABSTRACT

Objective: To know the perinatal outcomes in children of infected mothers during pregnancy Zika virus.
Materials and methods: An observational, descriptive, longitudinal retrospective study conducted at the Regional Hospital of High Specialty of Women (HRAEM) in Villahermosa Tabasco, from January 2016 to December 2017, included all pregnant women with Zika virus infection confirmed by the State Public Health laboratory using serum RT-PCR, who have completed pregnancy in the HRAEM. the variables studied were: the SDG and diagnostic quarter, ultrasound relationship according to biparietal diameter and cephalic perimeter according to gestational age, at birth the somatometry was evaluated, presence of congenital alterations, cephalic perimeter percentile for gestational age, was used as parameter to determine microcephaly the percentile <5 of the cephalic perimeter for gestational age.
Results: The total sample was 37 patients, with maternal age average of 25 years, with 17 of 37 detection in the first trimester of pregnancy, a proportional growth between weeks of gestation and cephalic measures during ultrasonographic follow-up was observed. One fetus was found below the 5th percentile of the biparietal diameter at 18.5 weeks, with dilation of the fourth ventricle and enlargement of the posterior fossa, images suggestive of probable Dandy Wallker syndrome. All other fetuses were found normal.
Conclusion: At birth, Dandy Wallker syndrome was confirmed in a patient secondary to trisomy 18 corroborated by karyotype. No congenital defects attributable to Zika virus were found in the rest of the patients.


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Ginecol Obstet Mex. 2019;87