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Federación Mexicana de Ginecología y Obstetricia, A.C.

2020, Number 02

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Ginecol Obstet Mex 2020; 88 (02)

Laparoscopic fertility-preserving surgery in borderline ovarian tumors. A case report

Noris-Martínez A, Pérez-López JC, García-Hernández GG, Martínez-Hernández CM, Mandujano-Álvarez GJ, Ramírez-López P

Language: Spanish
References: 13
Page: 111-117
PDF size: 224.10 Kb.


ABSTRACT

Background: Borderline ovarian tumors are defined as the presence of cell proliferation and nuclear atypia without stromal invasion2, their incidence is estimated between 2.5 and 5.5 / 100,000 women per year, they are usually diagnosed in early stages with a good prognosis even in advanced stages.
Clinical case: 25-year-old patient, with abdominal growth and diffuse pain, increased uterus of volume above the umbilical scar, with solid, mobile tumor, to the vaginal touch dependent on the right annex. Ultrasound report: right ovary 13.1 x 12 x 11.2 cm and the left not visible, CA 125: 130.4 U / mL. A peritoneal lavage was performed, a peritoneal biopsy was taken, and omentectomy and right salpingopherectomy were performed. The transoperative study reported the existence of a tumor in the right ovary, with implants in the abdominal cavity. Histopathological report: papillary tumor bordering the right ovary, without vascular invasion, peritoneal lavage, omentum and positive peritoneal implants to neoplastic cells. Adjuvant treatment with chemotherapy (Plaquitaxel and Carboplatin) was indicated and she managed to get pregnant a year after finishing that scheme; the pregnancy concluded in childbirth and birth of a girl of 3100 g.
Conclusion: This case reflects the success of laparoscopic surgery in the management of serous border tumors with fertility-preserving surgery, in addition to highlighting the use of chemotherapy as an adjuvant treatment in this type of pathologies.


REFERENCES

  1. Lou T, et al. The safety of fertility and ipsilateral ovary procedures for borderline ovarian tumors. Oncotarget. 2017;8(70): 18-29. doi: 10.18632/oncotarget.23021

  2. Ouldamer L, et al. Nomogram to predict live birth rate after fertility-sparing surgery for borderline ovarian tumours. Hum Reprod. 2016; 31(8): 1732-7. doi: 10.1093/ humrep/dew137.

  3. Mandelbaum RS, et al. Utero-ovarian preservation and overall survival of young women with early-stage borderline ovarian tumors. Arch Gynecol Obstet. 2019; 6: 1651-7. doi: https://doi.org/10.1007/s00404-019-05121-z

  4. Delle Marchette M, et al. Oncologic and fertility impact of surgical approach for borderline ovarian tumours treated with fertility sparing surgery. Eur J Cancer. 2019; 111: 61-8. doi: https://doi.org/10.1016/j.ejca.2019.01.021

  5. Li S, et al. Live births after in vitro fertilization with fertilitysparing surgery for borderline ovarian tumors: A case series and literature review. Gynecol Obstet Invest. 2019; 21: 1-10. doi: https://doi.org/10.1159/000497203

  6. Zhao J, et al. Short-term outcomes and pregnancy rate after laparoscopic fertility-sparing surgery for borderline ovarian tumors: A single-institute experience. Int J Gynecol Cancer. 2018; 28 (2): 274-8. doi: 10.1097/ IGC.0000000000001170

  7. Palomba S, et al. Ultra-conservative fertility-sparing strategy for bilateral borderline ovarian tumours: An 11- year follow-up. Hum Reprod. 2010; 25 (8): 1966-72. doi: 10.1093/humrep/deq159

  8. Gokcu M, et al. Borderline ovarian tumors: clinical characteristics, management, and outcomes: A multicenter study. J Ovarian Res. 2016; 9 (1): 1-8. https://doi.org/10.1186/ s13048-016-0276-1

  9. Ţarcă E, et al. Borderline ovarian cyst treated by laparoscopic surgery: Clinical case report and literature review. Rom J Morphol Embryol. 2015; 56 (4): 1529-34.

  10. Cadron I, et al. Management of borderline ovarian neoplasms. J Clin Oncol. 2007;25(20):2928–37. doi: 10.1200/ JCO.2007.10.8076

  11. Childress KJ, et al. Borderline Ovarian Tumor in the Pediatric and Adolescent Population: A Case Series and Literature Review. J Pediatr Adolesc Gynecol. 2018; 31 (1):48-54. doi: http://dx.doi.org/10.1016/j.jpag.2017.09.001

  12. Song T, et al. Minimally invasive compared with open surgery in patients with borderline ovarian tumors. Gynecol Oncol. 2017; 145 (3): 508-12. doi: http://dx.doi. org/10.1016/j.ygyno.2017.03.019

  13. Vasconcelos I, et al. A Meta-Analysis on the Impact of Platinum-Based Adjuvant Treatment on the Outcome of Borderline Ovarian Tumors With Invasive Implants. Oncologist. 2015; 20 (2): 151-8. doi: 10.1634/theoncologist. 2014-0144




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