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Federación Mexicana de Ginecología y Obstetricia, A.C.

2020, Number 06

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Ginecol Obstet Mex 2020; 88 (06)

Vaginal melanoma. A case report

Aguirre-García R, Peña-Vega CJ, García-Figueroa RB, Muñoz-Cortés SB, Alemán-Ceballos E, Arrecillas-Zamora MD

Language: Spanish
References: 11
Page: 402-406
PDF size: 328.40 Kb.


ABSTRACT

Background: Vaginal melanoma is an exceptional alteration, for which the diagnosis is established in advanced stages of the disease. The short-term prognosis is poor and there are no identified risk factors to date.
Clinical case: 77-year-old patient, who came to the clinic for fetid transvaginal bleeding, two months old. During colposcopy, a tumor was observed on the left lateral aspect of the vagina, which extended to its lower third; the anterior face was hyperpigmented and friable. Based on the cytology report and biopsy, the diagnosis of invasive melanoma was established. The concentration of tumor markers was positive for HMB-45, Ki 67 (20%), MART-1 (Melan-1) and PS-100. The patient was sent to the Oncology service for staging and treatment of the disease.
Conclusions: The identification of a hyperpigmented tumor on gynecological examination, in addition to a directed biopsy, complemented by an immunohistochemical study, is suggestive of vaginal melanoma. Patients with this type of injury should be cared for by a multidisciplinary medical team.


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