Gauna ME, Bernava JL

Language: Spanish
References: 5
Page: 60-63
PDF size: 726.18 Kb.

Text Extraction

The sudden emergence of COVID-19, with its ability of becoming a pandemic in such a few weeks, has challenged not only the health care systems but also many former concepts of medicine. This has forced us to act as quick as possible, not only to try to stop the progress of infections, but also to develop acting protocols which can reduce mortality.
Our colleagues from Spain and Italy were not warned about the situation they were about to face, but along these weeks, they have been passing to us their experiences, with their ups and downs, but always with the objective of preventing us from suffering the same they have. In Argentina, we had the blessing of a quick implementation of the compulsory quarantine and the possibility of preparing the health care system in the best possible way. Some of us could even sat to quietly read and analyze the information that our colleagues were sending us from the battlefield in Europe.
The following protocol is aimed to decrease the need of using mechanical ventilators as well as to reduce the mortality in the seriously ill patients. Bellow we explain the pathophysiology of the Thrombotic Immune Response Associated to COVID-19 (RITAC, by its abbreviation in Spanish), as we have decided to call it (Figure). When this pandemic ends, we will have the necessary time to gather and analyze the information that we will continue receiving in the next weeks.

REFERENCES

1. Mehta P, McAuley DF, Brown M, Sanchez E, Tat-tersall RS, Manson JJ. COVID-19: consider cyto-kine storm syndromes and immunosuppression. Lancet. 2020;395(10229):1033-4.

2. Tornero Molina J, Ballina García FJ, Calvo Alén J, Caracuel Ruiz MÁ, Carbonell Abelló J, López Me-seguer A, et al. Recomendaciones para el uso del metotrexato en artritis reumatoide: incremento y reducción de dosis y vías de administración. Reu-matol Clin. 2015;11(1):3-8.

3. Ministerio de Salud Argentina. Recomendaciones condicionales para el abordaje terapéutico de COVID-19 [Internet]. Buenos Aires: Ministerio de Salud Argentina; 2020 [citado 22 Mar 2020]. Dis-ponible en: https://www.argentina.gob.ar/salud/coronavirus-COVID-19/abordaje-terapeutico

4. Páramo Fernández JA. Coagulación, Dímero D y COVID-19: Una reflexión de Jose A. Páramo Her-nández, presidente de la Sociedad Española de Trombosis y Hemostasia (SETH) [Internet]. Ma-drid: Sociedad Española de Trombosis y Hemos-tasia [citado 22 Mar 2020]. Disponible en: https://www.seth.es/index.php/noticias/noticias/noticias-de-la-seth/1588-coagulacion-dimero-d-y-covid-19.html

5. Municio C, Dominguez-Soto Á, Fuentelsaz-Rome-ro S, Lamana A, Montes N, Cuevas VD, et al. Meth-otrexate limits inflammation through an A20-de-pendent cross-tolerance mechanism. Ann Rheum Dis. 2018;77(5):752-9