medigraphic.com
SPANISH

Revista Latinoamericana de Infectología Pediátrica

ISSN 2683-1678 (Print)
Órgano Oficial de la Sociedad
Latinoamericana de lnfectología Pediátrica.
Órgano de la Asociación Mexicana de
Infectología Pediátrica, A.C.
Órgano difusor de la Sociedad Española
de lnfectología
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2022, Number 1

<< Back Next >>

Rev Latin Infect Pediatr 2022; 35 (1)

Reversible posterior encephalopathic syndrome associated with Mycoplasma pneumoniae neuroinfection in a patient with acute lymphoblastic leukemia

Cardoso EHR, Velázquez DPX, Suárez HS, Fernández LCP
Full text How to cite this article 10.35366/104662

DOI

DOI: 10.35366/104662
URL: https://dx.doi.org/10.35366/104662

Language: Spanish
References: 12
Page: 26-29
PDF size: 175.32 Kb.


Key words:

Mycoplasma pneumoniae, encephalitis, reversible posterior encephalopathic syndrome.

ABSTRACT

We present the case of a 14-year-old male patient diagnosed with acute lymphoblastic leukemia on St. Jude total XV protocol, who began his illness with generalized tonic-clonic seizures, loss of alertness, systemic arterial hypertension, positive IgM for M. pneumoniae, and simple and contrasted cranial MRI with diffuse hyperintensity in T2 sequence and Fluid Attenuation Inversion Recovery (FLAIR) in bilateral superior and inferior cerebellar hemisphere of central predominance, to the administration of contrast with enhancement of the optic nerve path in its intracranial portion and right predominance. The literature describes the presence of encephalitis, cerebellitis or reversible posterior encephalopathic syndrome (RPES), associated with infection by M. pneumoniae, in this case this microorganism is detected with clinical and radiological signs of RPES, particularly in a patient with oncologic pathology, where the incidence or prevalence of this disease is not known with certainty.


REFERENCES

  1. Arkilo D, Pierce B, Ritter F et al. Diverse seizure presentation of acute Mycoplasma pneumoniae encephalitis resolving with immunotherapy. J Child Neurol. 2014; 29 (4): 564-5606.

  2. Christie L, Honarmand S, Talkington D et al. Pediatric encephalitis: What is the role of Mycoplasma pneumoniae? Pediatrics. 2007; 120 (2): 305-313.

  3. San Martin I, Urabayen R, Diez V et al. Síndrome de encefalopatía posterior reversible: 5 casos relacionados con quimioterapia. An Pediatr. 2014; 80 (2): 117-121.

  4. De Groot R, Meyer P, Unger W et al. Things that could be Mycoplasma pneumoniae. J Infect. 2017; 74 Suppl 1: S95-S100.

  5. Krafft K, Christy C. Mycoplasma pneumoniae in children and adolescents. Pediatr Rev. 2020; 41 (1): 12-19.

  6. Milstein N, Paret G, Reif S et al. Acute childhood encephalitis at 2 tertiary care children's hospitals in Israel etiology and clinical characteristics. Pediatr Emerg Care. 2016: 32 (2): 82-86.

  7. Smolders J, Jacobs B, Tio-Guillen A et al. Mycoplasma pneumoniae and antibodies against galactocerebroside in a 9-year-old boy with encephalitis. Neuropediatrics. 2019; 50 (1): 54-56.

  8. Ramgopal A, Thavamani A, Ghori A. Association between posterior reversible encephalopathy syndrome and Mycoplasma pneumoniae. J Pediatr Neurosci. 2018; 13 (1): 109-111.

  9. Meyer P, Moeller A, Relly C et al. Swiss national prospective surveillance of paediatric Mycoplasma pneumoniae associated encephalitis. Swiss Med Wkly. 2016; 146: w14222.

  10. Simpkins A, Strickland S, Oliver J et al. Complete resolution of advanced Mycoplasma pneumoniae encephalitis mimicking brain mass lesions: report of two pediatric cases and review of literature. Neuropathology. 2012; 91-99.

  11. Waites KB, Xiao L, Liu Y et al. Mycoplasma pneumoniae from the respiratory tract and beyond. Clin Microbiol Rev. 2017; 30 (3): 747-809.

  12. Arighi P, Deregibus MI, Agrimbau Vázquez J et al. Mycoplasma pneumoniae: manifestaciones neurológicas y controversias diagnósticas: a propósito de un caso. Arch Argent Pediatr. 2018; 116 (4): e590-e593.




Figure 1
Figure 2

2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Rev Latin Infect Pediatr. 2022;35