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2025, Number 2

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Acta Med 2025; 23 (2)

Post-extubation acute pulmonary edema due to negative pressure

Guillen OFC, Galván LFB, Medrano MA, Díaz BA
Full text How to cite this article 10.35366/119483

DOI

DOI: 10.35366/119483
URL: https://dx.doi.org/10.35366/119483

Language: Spanish
References: 3
Page: 172-174
PDF size: 200.88 Kb.


Key words:

pulmonary edema, extubation, thrombosis.

ABSTRACT

Acute negative pressure pulmonary edema (ANPPE) post-extubation, non-cardiogenic pulmonary edema, arises from negative intrathoracic pressure during forced spontaneous inspiration against a closed airway. Common in difficult intubations in healthy males, its incidence post-extubation is 0.1-0.9%. A 47-year-old female with no medical history underwent uneventful intubation for endourological surgery. Two hours after extubation, she exhibited respiratory distress, tachypnea, and desaturation (< 70%). Despite negative cardiac imaging, chest X-ray revealed pulmonary edema. Treatment involved a high-flow nasal cannula, loop diuretics, B agonists, and pulmonary therapy, resulting in a satisfactory recovery.


REFERENCES

  1. Ware LB, Matthay MA. Acute pulmonary edema. N Engl J Med. 2005; 353 (26): 2788-2796. Available in: http://dx.doi.org/10.1056/nejmcp052699

  2. Lemyze M, Mallat J. Understanding negative pressure pulmonary edema. Intensive Care Med. 2014; 40 (8): 1140-1143. Available in: http://dx.doi.org/10.1007/s00134-014-3307-7

  3. Ma J, Liu T, Wang Q, Xia X, Guo Z, Feng Q et al. Negative pressure pulmonary edema (Review). Exp Ther Med. 2023; 26 (3): 455. Available in: http://dx.doi.org/10.3892/etm.2023.12154




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C?MO CITAR (Vancouver)

Acta Med. 2025;23