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2025, Number 3

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Acta Med 2025; 23 (3)

Autoimmune encephalitis in pediatric patients: evaluation and treatment

Gutiérrez SDM, Arboleya DJ, Cedillo REM, Razo MMC, Pinto GLJ
Full text How to cite this article 10.35366/119958

DOI

DOI: 10.35366/119958
URL: https://dx.doi.org/10.35366/119958

Language: Spanish
References: 4
Page: 281-283
PDF size: 188.22 Kb.


Key words:

encephalitis, autoimmune, antibody, pediatric, NMDA-R.

ABSTRACT

Introduction: we present the case of a five-year-old female patient who presented to the emergency department with abnormal movements, including focal myoclonus in the right thoracic limb in the absence of fever. Notably, her parents reported recent behavioral changes and a regressive syndrome that had developed over the past two weeks. This paper examines the diagnostic process, the in-hospital progression including admission to the Pediatric Intensive Care Unit (PICU), and the response to targeted immunological treatment. Objective: to document and analyze the clinical presentation and approach taken by the pediatric service at Hospital Angeles México to raise awareness for future cases.


REFERENCES

  1. Abboud H, Probasco JC, Irani S, Ances B, Benavides DR, Bradshaw M et al. Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management. J Neurol Neurosurg Psychiatry. 2021; 92 (7): 757-768. Available in: https://jnnp.bmj.com/content/92/7/757.abstract

  2. García-Beristáin JC, Barragán-Pérez E, ChoperenaRodríguez R, Reyes-Cruz G. Encefalitis autoinmune en pediatría. Acta Pediatr Mex. 2017; 38 (4): 274-279.

  3. Carreto-Espinosa C, Enciso-Peláez S, Iglesias-Leboreiro J, Bernardez-Zapata I, Silva-Ramírez H, Escobedo-Berumen L et al. Encefalitis autoinmune: experiencia en el servicio de pediatría del Hospital Español de México. Rev Hosp Jua Mex. 2023; 90 (1): 1-7. Disponible en: http://dx.doi.org/10.24875/rhjm.22000027

  4. Cellucci T, Van Mater H, Graus F, Muscal E, Gallentine W, Klein-Gitelman MS et al. Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient. Neurol Neuroimmunol Neuroinflamm. 2020; 7 (2): e663. Available in: http://dx.doi.org/10.1212/nxi.0000000000000663




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Acta Med. 2025;23