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2026, Number 2

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Acta Med 2026; 24 (2)

Miller-Fisher syndrome in a patient with a history of Guillain-Barré after 40 years: a manifestation of the autoimmune neuropathy spectrum

Sosa RV, Neri PKD, Pinto GLJ, Calvo HMF
Full text How to cite this article 10.35366/122616

DOI

DOI: 10.35366/122616
URL: https://dx.doi.org/10.35366/122616

Language: Spanish
References: 4
Page: 133-134
PDF size: 169.96 Kb.


Key words:

Miller-Fisher, Guillain-Barré, ataxia, ophthalmoplegia, areflexia.

ABSTRACT

Introduction: Miller-Fisher syndrome is a variant of Guillain- Barré syndrome, distinguished by the clinical triad of ataxia, ophthalmoplegia, and areflexia. It can manifest several years after an initial episode of Guillain-Barré. Case report: a 54-yearold male with a history of Guillain-Barré syndrome at age 17 presented with ataxia, distal weakness, and ophthalmoplegia. Conclusion: Miller-Fisher syndrome should be included in the differential diagnosis of neurological emergencies to enable early diagnosis and optimize clinical outcomes.


REFERENCES

  1. Rocha Cabrero F, Morrison EH. Síndrome de Miller Fisher. En:StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025.

  2. Noioso CM, Bevilacqua L, Acerra GM, Della Valle P, Serio M,Vinciguerra C et al. Miller Fisher syndrome: an updated narrativereview. Front Neurol. 2023; 14: 1250774. doi: 10.3389/fneur.2023.1250774.

  3. Othman R, Abdallah M, Chalouhy G. A rare recurrence of Guillain-Barré syndrome. Cureus. 2024; 16 (6): e63006. doi: 10.7759/cureus.63006.

  4. Powers WJ, Rabinstein AA, Ackerson T, Adeoye OM, BambakidisNC, Becker K et al. Guidelines for the early management of patientswith acute ischemic stroke: 2019 update to the 2018 guidelinesfor the early management of acute ischemic stroke: a guidelinefor healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2019; 50 (12): e344-e418. doi:10.1161/STR.0000000000000211.




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Acta Med. 2026;24