2025, Number 4
Oral pyogenic granuloma as a manifestation of Klippel-Trénaunay syndrome: a literature review and case report
Vega GS, Espinoza OF, Torrealba MF, Contreras VL
Language: Spanish
References: 8
Page: 171-173
PDF size: 943.08 Kb.
ABSTRACT
Pyogenic granuloma is a common benign vascular lesion of the oral cavity, particularly on the gingiva, whose development is associated with local trauma, chronic irritants, hormonal changes, or certain medications. It is characterized by its rapid appearance, erythematous aspect, lobulated surface, and tendency to bleed. In contrast, Klippel-Trenaunay syndrome is a congenital disease that combines capillary, venous, and/or lymphatic malformations with hypertrophy of soft tissues and bone structures. The oral manifestation of this syndrome is uncommon, and the appearance of pyogenic granulomas in this context has been sparsely reported in the literature, which poses a diagnostic and therapeutic challenge. This article reviews the clinical, histopathological, pathophysiological, and genetic features of pyogenic granuloma and Klippel-Trenaunay syndrome, highlighting a possible pathogenic interaction between both conditions. This review provides the necessary theoretical framework for the subsequent presentation of a relevant clinical case.REFERENCES