Muñoz-Flores J, Santiago-González S

Language: Spanish
References: 30
Page: 79-85
PDF size: 608.80 Kb.

ABSTRACT

Introduction: residual choledocholithiasis occurs in at least 2% of cholecystectomized patients, with reports as high as 5 to 12%. Objective: to evaluate the predictive value of preoperative gamma glutamyl transferase and alkaline phosphatase in the diagnosis of residual choledocholithiasis. Material and methods: retrospective cohort study, with 178 patients, over 18 years of age, who underwent cholecystectomy. The statistical analysis was descriptive and inferential (logistic regression, ROC curves, Youden index). Results: the mean age was 43.85 years. 3.93% (n = 7) of patients had residual choledocholithiasis. The identified cut-off points, 91.5 U/l for gamma glutamyl transferase and 106 U/l for alkaline phosphatase, show high sensitivity (100 and 85.7%, respectively) and specificity (94.2 and 75.4%, respectively). Conclusions: preoperative gamma-glutamyl transferase and alkaline phosphatase levels are associated with asymptomatic choledocholithiasis. These enzymes may help identify patients who should undergo intraoperative cholangiography.

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