medigraphic.com
SPANISH

Archivos de Medicina de Urgencia de México

ISSN 2594-3006 (Electronic)
ISSN 2007-1752 (Print)
Archivos de Medicina de Urgencia de México
  • Contents
  • View Archive
  • Information
    • General Information        
    • Directory
  • Publish
    • Instructions for authors        
  • medigraphic.com
    • Home
    • Journals index            
    • Register / Login
  • Mi perfil

2026, Number 1

<< Back Next >>

Arch Med Urg Mex 2026; 18 (1)

Frequency of electrocardiographic abnormalities in patients with subarachnoid hemorrhage admitted to the emergency department of Regional General Hospital Nº 2

Palma-Vázquez K, Morales-Díaz GH
Full text How to cite this article 10.35366/123741

DOI

DOI: 10.35366/123741
URL: https://dx.doi.org/10.35366/123741

Language: Spanish
References: 36
Page: 26-31
PDF size: 325.93 Kb.


Key words:

subarachnoid hemorrhage, electrocardiographic alterations, emergencies.

ABSTRACT

Introduction: subarachnoid hemorrhage (SAH) is a critical neurological emergency with high mortality. The brain-heart interaction with neurocardiogenic dysfunction during the acute event produces electrocardiographic (ECG) alterations that can mimic coronary syndromes or progression to ventricular arrhythmias. Evidence in the Mexican population is limited.
Objective: to determine the frequency of alterations in the QTc, ST-segment and T-wave in patients with SAH admitted to the emergency department of the regional general hospital No. 2 (HGR No.2) of the Mexican Institute of Social Security (IMSS).
Methods: observational, descriptive and cross-sectional study carried out in patients over 18 years of age with SAH confirmed by Computed Tomography (CT), without previous heart disease, treated in the period between October 2024 and August 2025. 12-lead electrocardiograms were analyzed in the first 48 hours after admission to the emergency room. Descriptive statistics and inferential analysis were performed using chi-square (95% CI).
Results: 289 patients were included; 64.4% men. 39.8% showed ECG abnormalities. T-wave inversion was the most prevalent finding (31.8%) and QTc prolongation (6.9%). There was no significant association between sex and ECG abnormalities (p=0.378). A significant correlation was found between tomographic severity and the presence of abnormalities (p=0.000).
Conclusions: ECG abnormalities are common and proportional to the magnitude of subarachnoid hemorrhage. Close monitoring is vital for the comprehensive management and detection of myocardial complications in the emergency department.


REFERENCES

  1. Izurieta Carlos, Curotto-Grasiosi Joerge, Trossero Romina, CardúsMarta, “Intervalo QTc prolongado y taquicardia ventricularpolimórfica ligada a hemorragia subaracnoidea” Archivos de Cardiologíade México, Elsevier, 2013

  2. Yepez Fabián, Noroña Grace. Hemorragia subaracnoidea revisiónbibliográfica. Ciencia Latina. 2023;7(1):9279–93

  3. Fausto Vinicio Maldonado Coronel, “Hemorragia subaracnoideaaneurismática en la unidad de cuidados intensivos del HospitalLuis Vernaza Guayaquil, Ecuador” Revista Eugenio Espejo. 2019;13(1): 19-27.

  4. Carrillo-Esper Raúl, Carrillo Cordova Carlos Alberto, “Alteracioneselectrocardiográficas en hemorragias subaracnoidea por rupturade aneurisma. Reporte de un caso y revisión de literatura”, RevMex Anest 2007; 30:122-126.

  5. Ruben Sabogal-Barrios, “Hemorragia subaracnoidea aneurismática”iMedPub Journals, 2020, 16(6:17)

  6. Ahmed Adel, “Management of Subaracnoid Hemorrage” SpringerNature Suiza, 2022.

  7. Cabrera Diana. Trastornos electrocardiográficos en enfermedadesneurológicas. Revista colombiana de cardiología. 2001;11–21.

  8. Valerino James, Elson James. “Electrocardiographic Changes inCentral Nervous System Disease” Neurol Clin Neurocardiology.May 1993, 11: 2: 257-272.

  9. Al–Shahi R, White PM, Davenport RJ, Lindsay KW. Subarachnoidhaemorrhage. BMJ. 2006; 333:235– 40.

  10. Epidemiology of aneurysmal subarachnoid hemorrhage in Australiaand New Zealand: incidence and case fatality from the AustralasianCooperative Research on Subarachnoid HemorrhageStudy (ACROSS). Stroke 2000; 31: 1843- 1850.

  11. Braunwald E. Heart Disease, W. B. Saunders Company, Fourthedition 1992, p. 1810-1826.

  12. Talman William, Kelkar P, “Neural Control of the Heart: Central andPeripheral”. Neurol Clin Neurocardiology. May 1993; 11:2:239-256.

  13. Flanagan Daniel, Vaile Julian, et al., “The Autonomic Control ofHeart Rate an d insulin resistance in ypung adults” J Clin EndocrinolMetab 1999; 84:1263-7.

  14. Samuels Martin, “Neurally Induced Cardiac Damage” Neurol ClinNeurocardiology. May 1993; 11:2:273-292

  15. Cabrera Diana, “Endotelio e Insuficiencia Cardíaca” Rev Vol Cardiol1995; 4: 393-401.

  16. Ichinomiya Taiga, Terao Yoshiaki, Miura Kosuke, HigashijimaUshio, Tanise Tomomi, Fukusaki Makoto, et al. QTc interval andneurological outcomes in aneurysmal subarachnoid hemorrhage.Neurocrit Care. 2010;13(3):347–54.

  17. Brodde Otto-Erich, Bruck Heike, Leineweber Kirsten, SeyfarthTorsten. “Presence, distribution and physiological function of adrenergicand muscarinic receptor subtypes in the human heart.” BasicRes Cardiol. 2001;96(6):528–38.

  18. Van Bree Maurits, Roos Yvo, van der Bilt Ivo, Wilde Arthur, SprengersMarieke, de Gans Koen, et al. Prevalence and characterizationof ECG abnormalities after intracerebral hemorrhage. NeurocritCare. 2010;12(1):50–5.

  19. Sakr Yasser, Ghosn Issam, Vincent Jean Louis. Cardiac manifestationsafter subarachnoid hemorrhage: a systematic review of theliterature. Prog Cardiovasc Dis. 2002;45(1):67–80

  20. Brouwers Paul, Wijdicks Eelco, Hasan Djo, Vermeulen Marinus, et al.“Serial electrocardiographic recording in aneurysmal subarachnoidhemorrhage.” Stroke. 1989;20(9):1162–7.

  21. Frangiskakis Michael, Hravnak Marilyn, Crago Elizabeth, TanabeMasaki, Kip Kevin, Gorcsan John, et al. “Ventricular arrhythmiarisk after subarachnoid hemorrhage.” Neurocrit Care.2009;10(3):287–94.

  22. Takenaka Ichiro, Aoyama Kazuyoshi, Iwagaki Tamao, IshimuraHiroshi, Kadoya Tatsuo. “Development of torsade de pointes causedby exacerbation of QT prolongation during clipping of cerebralartery aneurysm in a patient with subarachnoid haemorrhage.” BrJ Anaesth. 2006 Oct;97(4):533-5.

  23. Fukui Shinji, Katoh Hiroshi, Tsuzuki Nobusuke, et al. “Multivariateanalysis of risk factors for QT prolongation following subaracnoidhemorrage” Crit Care. 2003; 7:R7-12.

  24. Classen Jan, Park Soojin, “Spontaneous subarachnoid hemorrhage”Lancet, 2022; Vol 400; P 846-862.

  25. Dasenbrock Hormuzdiyar, Rudy Robert, Smith Timothy, GuttieresDonovan, Frerichs Kai, Gormley William, et al. “Hospital-acquiredinfections after aneurysmal subarachnoid hemorrhage: A nationwideanalysis.” World Neurosurg. 2016; 88:459–74.

  26. Hammer Alexander, Ranaie Gholamreza, Erbguth Frank, HohenhausMatthias, Wenzl Martin, Killer-Oberpfalzer Monika, et al.“Impact of complications and comorbidities on the intensive carelength of stay after aneurysmal subarachnoid haemorrhage.” SciRep. 2020;10(1):6228.

  27. van der Bilt Ivo, Hasan Donovan, Vandertop William, Wilde Arthur,Visser Frans, et al. “Impact of cardiac complications on outcomeafter aneurysmal subarachnoid hemorrhage: a meta-analysis.”Neurology. 2009;72(7):635–42.

  28. Kerro Ali, Woods Timothy, Chang Jason. “Neurogenic stunned myocardiumin subarachnoid hemorrhage.” J Crit Care. 2017; 38:27–34.

  29. Medina de Chazal Horacio, Del Buono Marco, Keyser-MarcusLori, Ma Liangsuo, Moeller Gerard, Berrocal Daniel, et al. “Stresscardiomyopathy diagnosis and treatment: JACC state-of-the-artreview.” J Am Coll Cardiol. 2018;72(16):1955–71.

  30. Frangieh Antonio, Obeid Slayman, Ghadri Jelena-Rima, Imori Yoichi,D’Ascenzo Fabrizio, Kovac Marc, et al. “ECG criteria to differentiatebetween Takotsubo (stress) cardiomyopathy and myocardialinfarction.” J Am Heart Assoc. 2016;5(6).

  31. Lorsheyd Anouk, Simmers Timothy, Robles De Medina Etienne.“The relationship between electrocardiographic abnormalities andlocation of the intracranial aneurysm in subarachnoid hemorrhage.”Pacing Clin Electrophysiol. 2003;26(8):1722–8.

  32. Wilterdink Janet, Furie Karen, Easton Donald, “Cardiac Evaluationof Stroke Patients” Neurology, 1998;51: S23-S26.

  33. Huang, J. van Gelder, J.M.: The probability of sudden death fromrupture of intracranial aneurysms: a meta-analysis. Neurosurgery2002; 51: 1101-1105

  34. Valverde Minor, “Hemorragia subaracnoidea”, Revista Médica deCosta Rica y Centroamérica 2016,(619), 221-226.

  35. de Rooij, N.K., Linn, F.H., van der Plas, J.A., Algra, A., Rinkel, G.J.:Incidence of subarachnoid haemorrhage: a systematic review withemphasis on region, age, gender and time trends. J Neurol NeurosurgPsychiatry 2007; 78: 1365-1372.

  36. Muehlschlegel Susanne, “Subarachnoid hemorrhage”, Neurocriticalcare, 2018;24, 1623-1657.




CC BY-NC-ND

2020     |     www.medigraphic.com

Mi perfil

C?MO CITAR (Vancouver)

Arch Med Urg Mex. 2026;18