medigraphic.com
Organo Oficial de la Sociedad Mexicana de Urología

2026, Number 2

<< Back Next >>

Rev Mex Urol 2026; 86 (2)

Immediate, intermediate and late postoperative complications of kidney transplantation in a secondary care hospital: analysis of 13 years of experience (2005–2018)

Jaramillo-Mederos BB, Medrano-Serrano EI, Valenzuela-Espinoza JÁ, Camacho-Castro AJ, Osuna-Ramírez I, Sandoval-Guerrero O

Language: Spanish
References: 26
Page: 1-12
PDF size: 590.78 Kb.


ABSTRACT

Introduction: postoperative complications after kidney transplantation occur in up to 30 % of cases. In Mexico, despite an increase in procedures, data on outcomes and complication rates remain scarce.
Objective: to identify the main postoperative complications in patients undergoing kidney transplantation at a secondary-level hospital.
Materials and methods: an observational, analytical, retrospective study was conducted on patients with chronic kidney disease who underwent renal transplantation between 2005 and 2018 at a secondary-level hospital. The frequency and type of postoperative complications were analyzed. Descriptive and inferential statistics were applied using chi-square tests with relative risk at a 95 % confidence level and a 5 % margin of error.
Results: a total of 120 patients were included 65 % male, with a mean age of 43.3 ± 17.3 years. The overall prevalence of complications was 85 %. The most frequent were urological 43.7 %, infectious 40.5 %, vascular 19.1 %, wound-related 18.4 %, and drug-induced nephrotoxicity 10 %. Graft rejection occurred in 18.8 % of cases. Chronic graft nephropathy (OR=2.7; p=0.003), ureteral fistula (OR=2.6; p=0.016), recurrent urinary tract infection (OR=2.01; p=0.05), and vascular alterations (OR=6.22; p‹0.001) were the variables most associated with graft rejection.
Conclusions: a high prevalence of postoperative complications was observed among kidney transplant recipients, although mortality remained low. Early detection and appropriate management of these complications are crucial to improving graft survival and reducing morbidity.


REFERENCES

  1. Instituto Mexicano del Seguro Social. Guía dePráctica Clínica GPC Terapia Inmunosupresora enel Trasplante Renal. 2009.

  2. Dib-Kuri A, Aburto-Morales S, EspinosaÁlvarezA, Sánchez-Ramírez O. Trasplantesde órganos y tejidos en México. Revista deinvestigación clínica. 2005;57(2): 163–169.

  3. Centro Nacional de Trasplantes 3. Estadísticassobre donación y trasplantes: Informe anual 2019.2020.

  4. Méndez-Durán A, Ignorosa-Luna MH, Pérez-Aguilar G, Rivera-Rodríguez FJ, López-OcañaLR. La referencia a trasplante renal en el IMSS:un área de oportunidad para la mejora. RevistaMexicana de Trasplantes. 2017;6(1): 29–33.

  5. Martín P, Errasti P. Trasplante renal. Anales delSistema Sanitario de Navarra. 2006;29: 79–91.

  6. Loupy A, Aubert O, Orandi BJ, Naesens M,Bouatou Y, Raynaud M, et al. Prediction systemfor risk of allograft loss in patients receivingkidney transplants: international derivation andvalidation study. BMJ. 2019;366: l4923. https://doi.org/10.1136/bmj.l4923.

  7. Gioco R, Sanfilippo C, Veroux P, Corona D,Privitera F, Brolese A, et al. Abdominal wallcomplications after kidney transplantation:A clinical review. Clinical Transplantation.2021;35(12): e14506. https://doi.org/10.1111/ctr.14506.

  8. Kim PY, Shoghi A, Fananapazir G. RenalTransplantation: Immediate and LateComplications. Radiologic Clinics of NorthAmerica. 2023;61(5): 809–820. https://doi.org/10.1016/j.rcl.2023.04.004.

  9. Prudhomme T, Mesnard B, Abbo O, BanuelosB, Territo A, EAU – Young Academic Urologist(YAU) group of Kidney Transplantation andthe EAU – Young Academic Urologist (YAU)group of Paediatric Urology. Postoperativesurgical complications after pediatric kidneytransplantation in low weight recipients (<15 kg):a systematic review. Current Opinion in OrganTransplantation. 2023;28(4): 297–308. https://doi.org/10.1097/MOT.0000000000001074.

  10. Bharati J, Anandh U, Kotton CN, Mueller T,Shingada AK, Ramachandran R. Diagnosis,Prevention, and Treatment of Infections inKidney Transplantation. Seminars in Nephrology.2023;43(5): 151486. https://doi.org/10.1016/j.semnephrol.2023.151486.

  11. García-Cosío M D, Cruzado J M, Farrero M,Blasco Peiró M T, Crespo M, Delgado JiménezJ F, et al. Tratamiento de la cardiopatía enreceptores de trasplante renal: documento deconsenso nacional de SET/SEC/SEN basadoen una encuesta Delphi. Revista Española deCardiología. 2025;78(3): 252–262. https://doi.org/10.1016/j.recesp.2024.09.011.

  12. Rivera-Luna EN, Cruz-Santiago J, Meza-Jiménez G, Bernáldez-Gómez G, Moreno-LeyPI. Manejo perioperatorio en el receptor detrasplante renal. Hospital de EspecialidadesCentro Médico Nacional «La Raza» IMSS. RevistaMexicana de Trasplantes. 2016;5(1): 27–33.

  13. Asociación Médica Mundial. Declaración deHelsinki de la AMM – Principios éticos paralas investigaciones médicas con participanteshumanos. 2013.

  14. Diario Oficial de la Federación. NORMA OficialMexicana NOM-012-SSA3-2012, Que establecelos criterios para la ejecución de proyectos deinvestigación para la salud en seres humanos. 2013.

  15. Cámara de Diputados del H. Congreso de laUnión. Reglamento de la Ley General de Saluden Materia de Control Sanitario de Actividades,Establecimientos, Productos y Servicios. 1988.

  16. Molina J, Navas A, Agüera ML, RodríguezBenot A. Avances en inmunología del trasplanterenal. Nefrología. 2018;10(2): 11–19.

  17. Sardenberg T, Müller SS, Pereira HR, OliveiraRA, Hossne WS. Análisis de los aspectos éticosde la investigación en seres humanos contenidosen las instrucciones a los autores de 139 revistascientíficas brasileñas. Acta bioethica. 2000;6(2):293–307. https://doi.org/10.4067/S1726-569X2000000200008.

  18. Haberal M, Boyvat F, Akdur A, Kırnap M,Özçelik Ü, Yarbuğ Karakayalı F. SurgicalComplications After Kidney Transplantation.Experimental and Clinical Transplantation:Official Journal of the Middle East Society forOrgan Transplantation. 2016;14(6): 587–595.

  19. Dagnæs-Hansen J, Kristensen GH, StroombergHV, Rohrsted M, Sørensen SS, Røder A. SurgicalComplications Following Renal Transplantationin a Large Institutional Cohort. TransplantationDirect. 2024;10(6): e1626. https://doi.org/10.1097/TXD.0000000000001626.

  20. Yamanaka K, Kakuta Y, Nakazawa S, KobayashiK, Nonomura N, Kageyama S. Surgical andInfectious Complications Following KidneyTransplantation: A Contemporary Review.Journal of Clinical Medicine. 2025;14(10): 3307.https://doi.org/10.3390/jcm14103307.

  21. Dal Magro PS, Meinerz G, Garcia VD, Mendes FF,Marques MEC, Keitel E. Kidney transplantationand perioperative complications: a prospectivecohort study. Brazilian Journal of Anesthesiology.2024;74(6): 844556. https://doi.org/10.1016/j.bjane.2024.844556.

  22. Ounissi M, Gargah T, Barbouch S, BoubakerK, Cherif M, Bacha MM, et al. Acute tubularnecrosis in kidney transplantation. La TunisieMedicale. 2012;90(6): 463–467.

  23. Agrawal A, Ison MG, Danziger-Isakov L. Long-Term Infectious Complications of KidneyTransplantation. Clinical journal of the AmericanSociety of Nephrology: CJASN. 2022;17(2): 286–295. https://doi.org/10.2215/CJN.15971020.

  24. Khan I, Wani MA, Wani IA, Rather JI, Bhat MA,Wani MM, et al. Incidence of complications andoutcome in live kidney transplant recipients at 1year—a single center experience. The EgyptianJournal of Internal Medicine. 2025;37(1): 30.https://doi.org/10.1186/s43162-025-00414-z.

  25. Khan I, Wani MA, Wani IA, Rather JI, Bhat MA,Wani MM, et al. Incidence of complications andoutcome in live kidney transplant recipients at 1year—a single center experience. The EgyptianJournal of Internal Medicine. 2025;37(1): 30.https://doi.org/10.1186/s43162-025-00414-z.

  26. Barba Abad J, Rincón Mayans A, TolosaEizaguirre E, Romero Vargas L, Rosell CostaD, Robles García JE, et al. Complicacionesquirúrgicas en el trasplante renal y su influenciaen la supervivencia del injerto. Actas UrológicasEspañolas. 2010;34(3): 266–273.




2020     |     www.medigraphic.com