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ISSN 3122-3893 (Electronic)

2026, Number 2

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Rev Mex Traspl 2026; 15 (2)

Prevalence of acute kidney injury in liver transplantation and its association with risk factors in Hospital de Especialidades del Centro Médico Nacional La Raza

Canedo-Castillo NA, Gómez-Sánchez E, Mendoza-Mendoza GJ

Language: Spanish
References: 17
Page: 68-77
PDF size: 889.66 Kb.


ABSTRACT

Introduction: liver transplantation is a condition that alters the survival of patients with advanced cirrhosis. One of the main post-surgical complications is acute kidney injury (AKI), with a prevalence between 15% and 95%, which directly affects the length of stay in the ICU and is related to mortality. There are various pre-transplant, surgical, and post-surgical risk factors. Objective: to calculate the prevalence of AKI in liver transplant recipients treated in the intensive care unit and to determine the most important risk factors associated with AKI in these patients. Material and methods: this was an observational, retrospective, cross-sectional, single-center study with a 6-year exposure period. It included 77 liver transplant recipients. A bivariate analysis was performed comparing patients with and without AKI. Robot variance analysis (ROC): sensitivity and specificity were determined for risk factors with a p-value ‹ 0.20. Results: the observed prevalence was 62.3%. Grade 2 AKI was the most prevalent in our population at 24.6%. 12.9% required continuous renal replacement therapy. Furosemide was the most significant pre-surgical risk factor. The most frequent comorbidity was diabetes mellitus. Ischemia-reperfusion syndrome occurred in 66% of patients, and 48% were associated with AKI. Conclusions: the SOFA score is related to the presence and severity of AKI, and AKI is correlated with the length of stay in the ICU.


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