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Colegio de Medicina Interna de México.

2006, Number 4

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Med Int Mex 2006; 22 (4)

Influence of the systemic inflammatory response syndrome on the stay days in an ICU of patients with hypertensive illness of pregnancy

Duarte MJ, Díaz MS, Rubio GJ, Vargas GRB, Lee Eng CV, Fernández PLY

Language: Spanish
References: 17
Page: 272-277
PDF size: 307.57 Kb.


ABSTRACT

Objective: To determine the incidence of systemic inflammatory response in patients admitted in an intensive therapy unit with diagnosis of hypertensive illness associated to pregnancy (pre-eclampsia) and their complications (eclampsia and HELLP), as well as the influence of the systemic inflammatory response and the APACHE II score in the days of stay in the unit.
Material and methods: In a retrospective study, at the intensive care unit of a general hospital, the records of the patients admitted to the intensive therapy unit were analyzed in a period from January 1st, 1997 to December 31st, 2003. The presence of the systemic inflammatory response syndrome was determined, the patients also grouped about APACHE II score, and correlated with the days of stay in the unit.
Results: The records of 144 patients who entered to the intensive care unit were analyzed. Of which only 138 were included in the study. They were analyzed and they grouped to the patients as they completed or not approaches for the systemic inflammatory response syndrome and the APACHE II score to their entrance to the intensive care unit. It done APACHE II scores measurements and the days stay in the critical care unit. The mean age of the patients was of 25 years (SD 7), the mean gestational age was of 34 weeks (SD 4.6) and the mean of pregnancies was of 3 (SD 2.1) The resolution of the pregnancy was vaginal via in 13 patients (9%) and for cesarean surgery in 131 patients (91%), the mean of days stay was of 4.44 (SD 7.8). Different complications to those of the hypertension induced by the pregnancy were observed in 30 patients (20.8%). It was proven the presence of systemic inflammatory response syndrome in 37 patients (26%) with mean of day stays of 5.3 against 3.9 of the patients that didn’t develop the syndrome. (p = 0.0000028). The presence of the systemic inflammatory response syndrome caused the necessity for more days of stay in the group of patient with eclampsia (0.0029). Mortality was 2.1%.
Conclusion: The presence of systemic inflammatory response syndrome and the APACHE II score, influences mainly in the days of hospital stay in the patients with eclampsia and HELLP.


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