Padilla-Raygoza N, Alarcón-Ginori A, Figueroa-Ferrari RC, Muñoz-Rodríguez M

Language: Spanish
References: 8
Page: 196-199
PDF size: 134.17 Kb.

ABSTRACT

Objectives: The study was done in order to compare the effect of quinfamida vs nitazoxanida in the treatment of intestinal amebiasis.
Persons: 194 children were selected, among 865 which were attended to a private office of a pediatritian. All of them had cysts of entamoeba histolytic and present, at least, one gastrointestinal symptom or sign.
Methods: The children were distributed in two groups: one treated with quinfamida (n = 89) and the other with nitazoxanida (n = 105). At 5, 6 and 7 days of treatment the coproparasitoscopic studies were repeated. During the study the evolution of the children was recorded.
Results: The abdominal pain disapaered more frequently with the treatment of quinfamida. In the same way, de gastrointestinal manifestations and the disapaerison of cysts of amoeba in the feces, was more frequently found in childrens treated with quinfamida.
Conclusions: Quinfamida is a better option for the treatment of amebiasis in children.

REFERENCES

1. Muñoz O. Epidemiología de la amibiasis. En: Martínez A, ed. Amibiasis. México: Editorial Médica Panamericana 1989; 164-166.

2. Padilla-Raygoza N. Evolución natural de la amibiasis y sus niveles de prevención. Rev Mex Pediatr 1992; 59: 153-159.

3. Padilla N, Figueroa R, Rivera MR, Guerrero S. Amibiasis intestinal en el niño: estudio comparativo entre quinfamida y metronidazol. Rev Enf Infecciosas Pediatr 1994; 7: 2-6.

4. Padilla N, Figueroa R, Rivera MR, Guerrero S. Estudio comparativo entre quinfamida y etofamida en el tratamiento de la infección amibiana asintomática. Rev Mex Pediatr 1995; 62: 5-7.

5. Rossignol JF, Cavier R. New derivates of 2-benzarnido-5-nitrothiazoles: United States Patent-No. 3,950,351 April 13,1976.

6. Rossignol JF, Maisonneuve H, Cho YW. Nitroimidazoles in the treatment of trichomoniasis, giardiasis and, amebiasis. Inter J Clin Pharmacol Therap 1984; 22: 6372.

7. Biagi F. Amibiasis. En: Biagi F ed. Enfermedades. parasitarias. 2a ed, México: La Prensa Médica Mexicana 1988: 81-124.

8. Padilla N, Figueroa RC, Alarcón A, Rivera MR, Muñoz M. Estudio comparativo: una toma al día vs dos tomas al día de quinfamida en el tratamiento de la amibiasis intestinal asintomática en niños. Rev Enf Infecciosas Pediatr 1997; 11: 48-51.