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2015, Number 5

Salud Mental 2015; 38 (5)

Alteraciones neuropsicológicas por exposición crónica a concentraciones bajas de monóxido de carbono en trabajadores de autopista de peaje de México

Díaz-López LF, Haro-García LC, Juárez-Pérez CA, Aguilar-Madrid G
Full text How to cite this article

Language: Spanish
References: 26
Page: 353-359
PDF size: 170.08 Kb.


Key words:

Neuropsychological alterations, carboxyhemoglobin, CONSB, chronic occupational exposure, carbon monoxide.

ABSTRACT

Background Workers of the automobile industry, service stations and those working in the streets, are in chronic contact to low concentrations of carbon monoxide and at risk to damage the cardiovascular, haematology and nervous systems.
Objective Identify erythrocytosis and neuropsychological alterations in highway workers chronically exposed to low concentrations of CO.
Method Cross-sectional study that included 72 workers of the Mexico-Puebla Highway cabins (guards); 60 cashiers and 12 workers in charge of the shift, in which socio-demographic, clinical and occupational variables were explored; haemoglobin(Hb), hematocrit (Htc) and carboxyhemoglobin (COHb) was determined in their blood, and it was applied the Carbon monoxide neuropsychological screening battery (CONSB). The workers who are in charge of the full shift integrated the less exposed to CO group, while the cashiers would shape the greater exposure group.
Results In 49 workers, Hb: 18.1±1.9 mg/dL and Htc: 55.3±8.7 without significant differences between groups (p=0.82). The greater alteration was identified in the exposed group in the test of digit symbol (p= 0.012), trail-making part B (p= 0.002), and digit span (p=0.003); the test of blocks design resulted borderline (p=0.07).
Discussion and conclusion The group with the highest exposure to CO had lower performance in visual perception, encoding, visual-motor perception and immediate memory. Therefore important to consider epidemiological surveillance workers to intervene in cases with abnormal tests. The perception of innocuousness of chronic exposure to CO in these workers must avoid.


REFERENCES

  1. Stellman JM. Enciclopedia de salud y seguridad en el trabajo. Ginebra: OIT; 1998.

  2. Raub J. Environmental health criteria. Carbon monoxide. Ginebra: World Health Organization; 1999.

  3. Grandjean P, Nielsen GD. Biological indicators for the assessment of human exposure to industrial chemichals. Bruselas-Luxemburgo: Commission of the European Communities; 1997.

  4. Penney DG. A review: hemodynamic response to carbon monoxide. Environ Health Perspect 1988;77:121-130.

  5. Universidad de Oriente Núcleo Bolívar. Aspectos clínicos de intoxicación crónica por monóxido de carbono (CO) en trabajadores del terminal de pasajeros de Ciudad Bolívar. Estado de Bolívar: Escuela de Ciencias de la Salud; 2009.

  6. Lo CP, Chen SY, Lee KW, Chen WL et al. Brain injury after acute carbon monoxide poisoning: early and late complications. AJR 2007;189:W205–W211.

  7. Borras L, Constant E, De Timary P, Huguelet P et al. Long-term psychiatric consequences of carbon monoxide poisoning: A case report and literature review. La Revue Médecine Interne 2009; 30:43–48.

  8. Townsend CL, Maynard RL. Effects on health of prolonged exposure to low concentrations of carbon monoxide. Environ Med 2002; 59:708– 711.

  9. Pontificia Universidad Católica de Chile. Alteraciones neurológicas en intoxicación con monóxido de carbono. Cuadernos Neurología 2007; 31:1-7.

  10. Myers RAM, DeFazio A, Kelly MP. Chronic carbon monoxide exposure: a clinical syndrome detected by neuropsychological tests. J Clinical Psychology 1998; 54:555–567.

  11. Devine SA, Kirkley SM, Palumbo CL, White RF. MRI and neuropsychological correlates of carbon monoxide exposure: a case report. Environ Health Perspect 2002; 110:1051-1055.

  12. Rivas I, Salvatierra MG, Martín M, Hernández F. Aproximación diagnóstica y terapéutica a las eritrocitosis no clonales. Medicine 2008; 10:1354-1361.

  13. Katsumata Y, Aoki M, Sato K, Suzuhi O et al. A simple spectrophotometry for determination of carboxihemoglobin in blood. J Forensic Sci 1982; 27:928-34.

  14. Rabadán MJ, Román F, Sánchez MP. Neuropsicología. España: Diego Marín; 2010.

  15. Wendel B. Manual de pruebas neuroconductuales. Costa Rica: Diseños Precisos; 2000.

  16. Weshsler D. Escala Wechsler de inteligencia para adultos WAIS III, Manual de aplicación. México: Manual Moderno; 2003.

  17. Norma Oficial Mexicana nom-021-ssa1-1993. “Salud ambiental. Criterio para evaluar la calidad del aire ambiente con respecto al monoxido de carbono (CO)”. URL: http://www.salud.gob.mx/unidades/cdi/ nom/021ssa13.html (10 marzo 2014).

  18. Rojas M, Dueñas A, Sidorovas L. Evaluación de la exposición al monóxido de carbono en vendedores de quioscos. Pan Am J Public Health 2001; 9:241-245.

  19. Noel de Nevers. Ingeniería de control de la contaminación del aire; México: Edición McGraw Hill; 1997; p 503.

  20. Palacios AY, América L. Introducción a la toxicología ambiental. Metepec Edo. de México: ECO; 1997; p.123-147.

  21. Amitai Y, Zlotogorski Z, Golan-Katzav V, Wexler A et al. Neuropsychological impairment from acute low-level exposure to carbon monoxide. Arch Neurol 1998; 55:845-848.

  22. Weaver LK, Hopkins RO, Chan KJ, Churchill S et al. Hyperbaric oxygen for acute carbon monoxide poisoning. N Engl J Med 2002; 347:1057-1067.

  23. Lightfoot NF. Chronic carbon monoxide exposure. Proc Roy Soc Med 1972; 65:198-199.

  24. Amin S, Haq AUI, Noor M. Frequency of secondary polycythemia in chronic obstructive pulmonary disease. KJMS 2011; 3:62-64.

  25. Background on sources, symptoms, biomarkers and treatment of chronic carbon monoxide poisoning. URL: http:// www.mcsrr.org/resources/ articles/P11.html (10 marzo 2014)

  26. Thom SR. Antagonism of carbon monoxide-mediated brain lipid peroxidation by hyperbaric oxygen. Toxicol Appl Pharmacol 1990; 105:340-344.




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Salud Mental. 2015;38