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Colegio de Medicina Interna de México.

2019, Number 5

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Med Int Mex 2019; 35 (5)

Fulminant hepatic failure due to paracetamol

Rivas-Salazar RJ, Baltazar-Torres JÁ, Centurión-Mora SG

Language: Spanish
References: 18
Page: 789-794
PDF size: 416.57 Kb.


ABSTRACT

Acute liver failure is a rare disease but life-threatening, and occurs more frequently in patients without preexisting liver disease. Paracetamol (acetaminophen) is one of the analgesic-antipyretic drugs most frequently prescribed by physicians and selfmedicated by people, whose adverse effects are mild discomfort and even lethal side effects that do not necessarily require the toxic dose to cause such serious effects. Not surprisingly, acetaminophen remains a major cause of overdose: from intentional poisoning (suicide) and unintentional (chronic use), whose major effects are ranging from fulminant hepatic failure related to overdose to death; half of these episodes are attributable to paracetamol, and these cases seem to be increasing more and more, because of its easy access and free sale. The aim of this paper is to present a case report and a literature review.


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