Chapa AO, Arcos CH, Tessan KE , Carrero SH , Paz GFJ, Chapa IM , Elizalde DA

Language: Spanish
References: 14
Page: 122-128
PDF size: 167.30 Kb.

ABSTRACT

Introduction: Colorectal cancer in Mexico attracts the attention of 2^nd place in frequency between digestive system neoplasms, only more than gastric cancer. In death causes for cancer is placed in 6^th place. More effective primary treatment for colorectal carcinoma is still complete surgical resection. The survival to 5 years of colorectal cancer patients treated in early stage (stage I, Tis/1, N0, M0) is more 90% according to different published series. However, less than 39% of patients with colorectal cancer are in early stages in moment of diagnostic. Recently, several authors had analyzed incidence of malignant free cells in peritoneum in patients with colorectal cancer at moment of surgery, and its possible impact over the prognostic in patients in stage II (T3/4, N0, M0). The aim of this study is to determine if the transoperatory peritoneal cytology must be realized in routine way in patients with colon cancer; in case of be positive tumor cells is necessary to change therapeutic management; and if survival thumb index in the patient to modify after surgical resection “curative” apparently. Methods and patients: A prospective study, descriptive longitudinally, in patients with diagnosis of colon cancer stage II (T2/3, N0, M0) attend from November 2005 to December 2005 in surgery service who where made exploratory laparotomy with transoperatory peritoneal cytology and colon resection according to the case. Results: Histopathology diagnosis where moderately differentiated adenocarcinoma in 7 patients (100%). The tumor was to localize in cecum 5 patients (72%), transverse colon 1 patient (14%) and sigmoid colon in 1 patient (14%). Conclusion: Literature reports from 5 to 15% of positive cytology’s in patients with “curative” resections of colon cancer in stage II, it’s demonstrated that neoplasia free cells in peritoneum represents bad prognostic indicating for this patients, and who including have some importance than presence of metastases in regional nodes therefore. 1. We think that conventional transoperatory cytology is a implement useful in colorectal cancer treatment, therefore, must be realized as routine in all patients who had undergo to “curative” resection. 2. In case of are positive if therapeutic management changes, because of the patients can be undergo or adjuvant therapy. 3. In case of be positive if impinge on tumor recurrence and changes the survival thumb index 5 years of patients.

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